This page may have documents that can’t be read by screen reader software. For help with these documents, please call 1-800-203-3765.

Special Requirements and Limitations for Certain Medications

Medications That Must Be Pre-approved

Under the Prior Authorization Program, your doctor needs approval from Blue Cross and Blue Shield of Illinois before your prescription drug plan will cover certain medications and drug categories.

Preauthorization Request Form

Medications That Require a Prescription History

The Step Therapy Program encourages safe, cost-effective medication use by requiring you to have a prescription history for a "first-line" medication before your benefit plan will cover a "second-line" drug.

A first-line drug is recognized as safe and effective in treating a specific medical condition, as well as being a cost-effective treatment option. A second-line drug is a less-preferred or potentially more costly treatment option.

Check the Basic Drug List or visit MyPrime to see if any special requirements apply for your drug(s). If you're a current member and have recently gone through the Step Therapy Program for a particular drug, you don't have to complete it again.

Requirements for Specialty Medications

Specialty medications include those used in the treatment of complex medical conditions. Examples include hepatitis C, hemophilia, multiple sclerosis and rheumatoid arthritis.

Through the Prime Specialty Pharmacy, you can have self-administered specialty drugs delivered directly to you or your doctor's office.*

View the Specialty Pharmacy Program Drug List which includes a reminder about coverage for self-administered specialty medications.

Note: If you use a manufacturer’s coupon to help reduce how much you pay for a specialty drug, the value of that coupon will not be applied toward your coinsurance (or deductible, if you have a High Deductible Heath Plan) and yearly out-of-pocket (OOP) maximum.

To order through Prime Specialty Pharmacy:

  • For new prescriptions – Ask your doctor to call in your prescription to 1-877-627-MEDS (6337) or fax it in to 1-877-828-3939.
  • For existing prescriptions – You can transfer your existing prescription for a specialty medication by calling 1-877-627-MEDS (6337).

*A Prime Specialty Pharmacy coordinator will contact you to arrange delivery of your medication with each order.

Requirements for Generic Medications

Some brand-name drugs are also available in a generic version. If your medication is available in a generic version with the same active ingredients and at the same dosage you'll pay more if you choose to buy the brand-name version. In that case, you'll pay your higher copayment or coinsurance amount, plus the difference in cost between the brand drug and its generic equivalent. When you can, buying the generic version can often save you money.

Requirements for Over-The-Counter (OTC) Equivalent Exclusion Program

Keep in mind medications that can also be found over-the-counter (OTC) are usually not covered through your prescription drug plan, even if your doctor has prescribed it. Because these drugs are not covered under your plan, buying the OTC version can often save you money.

Dispensing Limits for Certain Medications

To help ensure safe drug usage, there are rules put on certain medications. These rules affect:

  • The amount of medication allowed per prescription
  • The amount of medication allowed in a time period
  • Coverage available only for patients between certain ages

These limits reflect generally accepted pharmaceutical manufacturers' guidelines and help encourage medication use as intended by the U.S. Food and Drug Administration (FDA).

For more information, view Dispensing Limits.